A. being crucial for GSK682753A inverse agonism because Ala substitution resulted in a >500-fold decrease in IC50. In conclusion, we present the first ligand targeting EBI2. In turn, this molecule provides a useful tool for further characterization of EBI2 MAP2K2
We found that this ubiquitination was abrogated with the ubiquitin mutant in which a lysine at position 63 (K63R), but not at position 48 (K48R), was mutated to arginine (Number 5C)
We found that this ubiquitination was abrogated with the ubiquitin mutant in which a lysine at position 63 (K63R), but not at position 48 (K48R), was mutated to arginine (Number 5C). compared to control cells or solitary knockdown cells. These