Characterizing function of a trait-associated 3′-UTR variant with transfectedCHGA3′-UTR/luciferase reporter plasmids

Characterizing function of a trait-associated 3′-UTR variant with transfectedCHGA3′-UTR/luciferase reporter plasmids. == Results == CHGA was overexpressed in patients with hypertension, especially hypertensive men, and CHGA predicted catecholamines. cell-transfectedCHGA3′-UTR/luciferase reporter plasmid, the +87T allele associated with lower BP also decreased